29 October 2014, 7:10 am
While international rhetoric on HIV and AIDS frequently invokes human rights, putting these ideas into practice in specific settings remains challenging, according to a process evaluation of an intervention in rural South Africa published in the October issue of Culture, Health and Sexuality. Although female health volunteers understood gender inequalities to be a key


28 October 2014, 8:00 am
Prevalence of transmitted drug-resistant HIV has doubled in low- and middle-income countries in recent years, results of a meta-analysis published in AIDS show. Between 2004-08 and 2009-13, rates of transmitted resistance increased markedly in all key populations in these settings. The increase coincides with the expanded roll-out of antiretroviral therapy (ART) in resource-limited settings; however


27 October 2014, 8:30 am
Use of the new anti-tuberculosis (TB) drug bedaquiline as part of a tailored regimen achieved high rates of culture conversion in people with multidrug-resistant TB (MDR-TB) and extensively drug-resistant TB (XDR-TB), French investigators report in the online edition of Clinical Infectious Diseases. The study population comprised 35 people who were provided with compassionate access to the drug


24 October 2014, 7:20 am
AbbVie's 3D hepatitis C regimen containing paritaprevir (ABT-450), ombitasvir, and dasabuvir was generally well-tolerated in the Phase 3 PEARL trials, according to a pooled analysis presented at IDWeek 2014 earlier this month in Philadelphia, United States. Serious side-effects were uncommon and few people discontinued treatment for this reason. Direct-acting antiviral agents have brought about a revolution in


23 October 2014, 8:00 am
Though there has been improving performance of healthcare delivery at each point of the HIV care cascade, from linkage to care through viral suppression, "success varies significantly by age and gender, even in an integrated care system with equal access to care,” Michael Horberg of the Mid-Atlantic Permanente Research Institute reported earlier this month at


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