23 July 2014, 1:40 pm
An NRTI-sparing dual antiretroviral regimen containing maraviroc (Celsentri) plus ritonavir-boosted darunavir (Prezista) was found to be less effective than a standard combination with tenofovir/emtricitabine (the drugs in Truvada), according to findings from the MODERN study presented this week at the 20th International AIDS Conference (AIDS 2014) in Melbourne. Combination antiretroviral therapy (ART) typically consists of two nucleoside/nucleotide reverse


23 July 2014, 9:50 am
There are significant losses at each step of the post-exposure prophylaxis (PEP) ‘treatment cascade’, according to a systematic review and meta-analysis of 97 studies presented to the 20th International AIDS Conference (AIDS 2014) in Melbourne yesterday. The problems with uptake, adherence and completion point to a need for a simplified approach, comment the authors.PEP


23 July 2014, 7:40 am
Laws which criminalise homosexual behaviour – such as those recently passed by Nigeria and Uganda – are not just symbolic or rarely put into practice, a global survey shows. One in twelve men who have sex with men (MSM) who responded to a global survey had been arrested or convicted


22 July 2014, 4:50 pm
The first results published from the IPERGAY study, a trial of pre-exposure prophylaxis (PrEP) in gay men taking place in France and Quebec, Canada, appear to indicate excellent adherence to a novel ‘pre-and-post’ intermittent PrEP strategy designed to save money and reduce time spent taking PrEP unnecessarily. The results were presented at the


22 July 2014, 4:40 pm
Two presentations at the 20th International AIDS Conference (AIDS 2014) in Melbourne described new pathways being explored in the search for either a permanent cure for HIV or for longer-acting drugs. In one, two artificial genes that cause cells to generate antiviral entry inhibitors produced significant inhibition of cellular infection. In another, a technique that is


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