15 April 2015, 10:00 am
Annual CD4 count monitoring may be sufficient for people taking antiretroviral treatment who have a suppressed viral load and a CD4 count above 250 cells/mm3, investigators report in the online edition of the Journal of Acquired Immune Deficiency Syndromes. Their study showed that people in this situation had a very low risk of


14 April 2015, 8:00 am
Changes to an individual’s risk profile – including starting to have unprotected sex with a steady partner, a partner being diagnosed with HIV and having a new diagnosis of syphilis – are associated with an increased risk of HIV seroconversion in the following months, according to an analysis of incidence in a cohort of


13 April 2015, 7:50 am
A combination regimen containing high-dose rifampicin (also known as rifampin) was associated with faster tuberculosis (TB) bacteria culture conversion in people with drug-sensitive TB, but moxifloxacin and the experimental drug SQ109 showed no benefit compared to standard therapy, according to results from a study presented at the recent Conference on Retroviruses and Opportunistic Infections (CROI 2015) in Seattle, USA. An


10 April 2015, 7:20 am
Post-study interviews and computer questionnaires conducted with former participants in a trial of pre-exposure prophylaxis (PrEP) that reported zero effectiveness show that participants concealed their low adherence to the study pills because, despite reassurances from researchers, they feared they would be asked to leave the study. The interviews reveal that some participants went to elaborate


9 April 2015, 7:30 am
Opioid substitution treatment (OST) increases the chances of people who inject drugs achieving good adherence to highly active antiretroviral therapy (HAART) by 68%, Canadian investigators report in the online edition of AIDS. Researchers monitored 1852 people living with HIV, who were injecting drugs and who were eligible for HIV treatment, for an average


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