25 March 2015, 6:10 pm
There is evidence of increasing interest in HIV treatment as prevention among people living with HIV in the UK, with the number of people starting treatment at high CD4 cell counts doubling over a five-year period, according to data presented at a Public Health England meeting this week. In 2013, 49% of those starting


25 March 2015, 7:40 am
The scale-up of antiretroviral therapy (ART) in Kenya is being undermined by high rates of treatment failure, investigators report in the online edition of the Journal of Acquired Immune Deficiency Syndromes. Over a third of patients failed first- and second-line therapy. Use of inappropriate regimens and lack of adherence support were associated with failure to


24 March 2015, 10:40 am
Starting antiretroviral therapy (ART) very soon after infection may limit the size of the HIV 'reservoir' and delay viral rebound after treatment interruption, according to several presentations at the recent Conference on Retroviruses and Opportunistic Infections (CROI 2015) in Seattle, USA. Other research showed that various biomarkers may predict who will experience HIV rebound after


24 March 2015, 10:40 am
Researchers at the recent Conference on Retroviruses and Opportunistic Infections (CROI 2015) in Seattle, USA, presented data on several experimental agents that may play a role in achieving a 'functional cure' for HIV, or prolonged remission without disease progression. These include drugs that reactivate the latent HIV reservoir, interfere with expression of viral DNA and help


24 March 2015, 7:30 am
Screening and treatment for cryptococcal meningitis combined with a short period of adherence support has the potential to significantly reduce mortality rates among people with very low CD4 counts starting antiretroviral therapy (ART) in resource-limited settings, investigators report in The Lancet. Twelve-month mortality rates were 28% lower for patients who received the enhanced care package including


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