30 October 2014, 9:30 am
Researchers have determined the dose of an injectable formulation of the integrase inhibitor cabotegravir (formerly GSK744) that will be taken into efficacy trials to see if it can be used for pre-exposure prophylaxis (PrEP). Studies in animals were presented earlier this year suggesting that drug levels stayed high enough in the body for it to


30 October 2014, 9:30 am
The risk of acquiring herpes simplex virus type 2 (HSV-2) was reduced by 46% (aIRR:0.54, 95%CI:0.30-0.97, p=0.038) among women who regularly used the vaginal gel containing tenofovir, according to a secondary analysis of the Vaginal and Oral Interventions to Control the Epidemic (VOICE) trial presented at the HIV Research for Prevention conference (R4P) in Cape Town,


30 October 2014, 8:00 am
Increased expenditure on social protection programmes – sickness, disability and unemployment benefits, old age pensions, housing support – is associated with improved tuberculosis (TB) control, according to an analysis of data from European Union (EU) countries published in Lancet Infectious Diseases. “Social protection spending is strongly associated with lower tuberculosis case notification, incidence, and mortality rates,” comment the


29 October 2014, 10:50 am
“There’s only one Berlin patient still. But by this time next year he will at least be joined by 40-50 Portland monkeys.” This was vaccine researcher Louis Picker, summarising in quotable form why the outlook for the development of an effective HIV vaccine is brighter than it has been for years, in a satellite session


29 October 2014, 8:30 am
In an extraordinary development, a second European scientific trial of pre-exposure prophylaxis (PrEP) has had its randomised phase closed early due to high effectiveness, just two weeks after the UK PROUD trial did exactly the same thing. The investigators of the IPERGAY trial, which has six sites in France and one in Canada, announced today a “Significant


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